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危险化学品

收录危险化学品目录,并提供相应的化学品安全技术说明书(Material Safety Data Sheet,简称MSDS)。用户可获取化学品的理化参数、燃爆性能、对健康的危害、安全使用贮存、泄漏处置、急救措施以及有关的法律法规等十六项内容。为实验室安全提供重要参考。

  



                


* * * Section 1 - PRODUCT AND COMPANY IDENTIFICATION  * * *


Material Name: 

ANILAZINE


ChemADVISOR, Inc.
Stone Quarry Crossing 811 Camp Horne Road, Suite 220 Pittsburgh, PA 15237
E-mail: info@chemadvisor.com MSDS is for reference use only; please contact manufacturer for emergency response information, routine product inquiries and orders.








Chemical Family 

oxazines 


Synonyms 

1,3,5-TRIAZIN-2-AMINE, 4,6-DICHLORO-N-(2-CHLOROPHENYL)-; S-TRIAZINE, 2,4-DICHLORO-6-(O-CHLOROANILINO)-; 4,6-DICHLORO-N-(2-CHLOROPHENYL)-1,3,5-TRIAZIN-2-AMINE; 2,4-DICHLORO-6-(O-CHLOROANILINO)-S-TRIAZINE; 2-CHLORO-N-(4,6-DICHLORO-1,3,5-TRIAZIN-2-YL)ANILINE; 2,4-DICHLORO-6-(2-CHLOROANILINO)-1,3,5-TRIAZINE; (O-CHLOROANILINO)DICHLOROTRIAZINE; ANILAZIN; ANIYALINE; B-622; BORTRYSAN; DYRENE; KEMATE; TRIAZIN; ZINOCHLOR; NCI-C08684; ENT 26,058; C9H5CL3N4









* * * Section 2 - HAZARDS IDENTIFICATION  * * *


Emergency Overview 

Color:  white to brown 

Change in color: Not available

Physical Form: crystals

Health Hazards:  skin irritation 




Potential Health Effects 
Inhalation 

Short Term:  mild irritation 

Long Term:  no information is available 




Skin Contact 

Short Term:  irritation 

Long Term:  no information on significant adverse effects 




Eye Contact 

Short Term:  mild irritation 

Long Term:  no information is available 




Ingestion 

Short Term:  no information on significant adverse effects 

Long Term:  no information on significant adverse effects 















* * * Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS  * * *


CAS EC No Registration NoComponent Name Synonyms1272/2008 (CLP)Percent
101-05-3 202-910-5 --ANILAZINESkin Irrit. 2 - H315 Eye Irrit. 2 - H319 Aquatic Acute 1 - H400 Aquatic Chronic 1 - H410100











* * * Section 4 - FIRST AID MEASURES  * * *


Inhalation 

If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. Get immediate medical attention. 


Skin 

Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention, if needed. Thoroughly clean and dry contaminated clothing and shoes before reuse. 


Eyes 

Flush eyes with plenty of water for at least 15 minutes. Then get immediate medical attention. 


Ingestion 

Get medical attention immediately. 


Note to Physicians 

For ingestion, consider gastric lavage and catharsis. Consider oxygen. 









* * * Section 5 - FIRE FIGHTING MEASURES  * * *


See Section 9 for Flammability Properties 

NFPA Ratings: 
Health: 2 Fire: 1 Reactivity: 0

Hazard Scale: 0 = Minimal 1 = Slight 2 = Moderate 3 = Serious 4 = Severe




Flammable Properties 

Slight fire hazard. 


Extinguishing Media 

regular dry chemical, carbon dioxide, water, regular foam Large fires: Use regular foam or flood with fine water spray. 


Fire Fighting Measures 

Move container from fire area if it can be done without risk. 









* * * Section 6 - ACCIDENTAL RELEASE MEASURES  * * *


Occupational spill/release 

Do not touch spilled material. Stop leak if possible without personal risk. Small spills: Absorb with sand or other non-combustible material. Collect with absorbent into suitable container. Small dry spills: Collect spilled material in appropriate container for disposal. Move containers away from spill to a safe area. Large spills: Dike for later disposal. Keep unnecessary people away, isolate hazard area and deny entry. 









* * * Section 7 - HANDLING AND STORAGE  * * *


Storage Procedures 

Store and handle in accordance with all current regulations and standards. May be subject to EPA pesticide registration. Keep separated from incompatible substances. 









* * * Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION  * * *


Component Exposure Limits 

ACGIH, NIOSH, EU, OSHA (US) and Mexico have not developed exposure limits for any of this product's components 




Component Analysis 

Biological limit value 

There are no biological limit values for any of this product's components. 




Ventilation 

Provide local exhaust ventilation system. Ensure compliance with applicable exposure limits. 


PERSONAL PROTECTIVE EQUIPMENT 

Eyes/Face Wear splash resistant safety goggles. Provide an emergency eye wash fountain and quick drench shower in the immediate work area. 


Protective Clothing 

Wear appropriate chemical resistant clothing. 


Glove Recommendations 

Wear appropriate chemical resistant gloves. 


Respiratory Protection 

Under conditions of frequent use or heavy exposure, respiratory protection may be needed. Respiratory protection is ranked in order from minimum to maximum. Consider warning properties before use. Any air-purifying half-mask respirator equipped with organic vapor cartridge(s) in combination with an N95, R95, or P95 filter. The following filters may also be used: N99, R99, P99, N100, R100 or P100. Any air-purifying full-facepiece respirator (gas mask) with a chin-style, front-mounted or back-mounted organic vapor canister having an N100, R100, or P100 filter. Any powered, air-purifying respirator with a tight-fitting facepiece, organic vapor cartridge(s) and high-efficiency particulate filter(s). Any supplied-air respirator with a full facepiece that is operated in a pressure-demand or other positive-pressure mode. For Unknown Concentrations or Immediately Dangerous to Life or Health - Any supplied-air respirator with a full facepiece that is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode. Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. 









* * * Section 9 - PHYSICAL AND CHEMICAL PROPERTIES  * * *


Appearance Not available Physical State Solid
Odor Not available Color white to brown
Odor Threshold Not available pH Not available 
Melting Point 159 - 160 °CBoiling Point Not available 
Freezing point Not available Evaporation Rate Not available 
Boiling Point Range Not available Flammability (solid, gas) Not available 
Autoignition Not available Flash Point Not available 
Lower Explosive Limit Not available Decomposition Not available 
Upper Explosive Limit Not available Vapor Pressure Not available 
Vapor Density (air=1) Not available Specific Gravity (water=1) Not available 
Water Solubility (insoluble)Partition coefficient: n-octanol/water Not available 
Viscosity Not available Solubility (Other) Not available 
Density Not available Physical Form crystals
Molecular Formula CL2-N3-C3-N-H-C6-H4-CLMolecular Weight 275.51




Solvent Solubility 
Soluble 

acetone, hydrocarbons, chlorinated solvents, organic solvents 


Slightly Soluble 

toluene, xylene, chlorobenzene 













* * * Section 10 - STABILITY AND REACTIVITY  * * *


Chemical Stability 

Stable at normal temperatures and pressure. 


Conditions to Avoid 

Avoid heat, flames, sparks and other sources of ignition. Avoid generating dust. Keep out of water supplies and sewers. 


Incompatible Materials 

bases, combustible materials, 


ANILAZINE: ALKALINE COMPOUNDS: Hydrolysis may occur when heated. OILS: Incompatible.

Hazardous Decomposition Products 

oxides of nitrogen, carbon, halogenated compounds 


Thermal decomposition products: oxides of nitrogen, carbon, chlorides.

Possibility of Hazardous Reactions 

Will not polymerize. 









* * * Section 11 - TOXICOLOGICAL INFORMATION  * * *


Component Analysis - LD50/LC50 

The components of this material have been reviewed in various sources and the following selected endpoints are published: 
ANILAZINE (101-05-3)

Oral LD50 Rat 2700 mg/kg

Dermal LD50 Rabbit >9400 mg/kg

Inhalation LC50 Rat >228 mg/m3 1 h




Component Carcinogenicity

None of this product's components are listed by ACGIH, IARC, NTP, DFG or OSHA




Inhalation - Acute Exposure 

ANILAZINE Some triazines are mildly irritating to the upper respiratory tract.


Inhalation - Chronic Exposure 

ANILAZINE No data available.


Skin Contact - Acute Exposure 

ANILAZINE: 0.1% applied to human skin was moderately irritating 9.4 gm/kg of anilazine applied to the rabbit skin in the form of a paste (in peanut oil or dimethyl phthalate) produced local erythema, edema, ulceration, fissuring, and incrustation; systemic effects of toxic degenerative changes in the liver and kidneys also occurred.


Skin Contact - Chronic Exposure 

ANILAZINE Prolonged skin contact may cause irritation.


Eye Contact - Acute Exposure 

ANILAZINE Some triazines are mildly irritating to the eyes.


Eye Contact - Chronic Exposure 

ANILAZINE No data available.


Ingestion - Acute Exposure 

ANILAZINE A lethal dose in rats was 2700 mg/kg; symptoms were not reported.


Ingestion - Chronic Exposure 

ANILAZINE: Toxic degeneration of liver and kidneys was observed in a 77-day study of rats fed 30 and 70 mg/kg/day Weight loss, enlargement of the liver, kidney, and spleen, and death were reported from a study of dogs fed 1.0 gm/kg/day over a period of 681 days.









* * * Section 12 - ECOLOGICAL INFORMATION  * * *


Component Analysis - Aquatic Toxicity 

ANILAZINE101-05-3
Fish: LC50 96 h Oncorhynchus mykiss 0.122 - 0.161 mg/L [static]; LC50 96 h Lepomis macrochirus 0.142 - 0.735 mg/L [static]
Algae: EC50 72 h Pseudokirchneriella subcapitata 2.51 mg/L IUCLID
Invertebrate: EC50 48 h Daphnia magna 0.56 - 1.8 mg/L EPA















* * * Section 13 - DISPOSAL CONSIDERATIONS  * * *


Disposal Methods 

May be subject to EPA pesticide registration. May be subject to EPA pesticide registration. Dispose in accordance with all applicable regulations. 


Component Waste Numbers 

The U.S. EPA has not published waste numbers for this product's components 











* * * Section 14 - TRANSPORT INFORMATION  * * *


US DOT Information:

No Classification assigned.




TDG Information:

No Classification assigned.




ADR Information:

No Classification assigned.




RID Information:

No Classification assigned.




IATA Information:

No Classification assigned.




ICAO Information:

No Classification assigned.




IMDG Information:

No Classification assigned.

Component Marine Pollutants (IMDG) 

Not regulated as dangerous goods. 















* * * Section 15 - REGULATORY INFORMATION  * * *


US Federal Regulations 
This material contains one or more of the following chemicals required to be identified under SARA Section 302 (40 CFR 355 Appendix A), SARA Section 311/312 (40 CFR 370.21), SARA Section 313 (40 CFR 372.65), CERCLA (40 CFR 302.4), TSCA 12(b), and/or require an OSHA process safety plan 
ANILAZINE101-05-3
SARA 313: 1 % de minimis concentration




SARA Section 311/312 (40 CFR 370 Subparts B and C) 

Acute Health: Yes Chronic Health: No Fire: No Pressure: No Reactivity: No








U.S. State Regulations 
The following components appear on one or more of the following state hazardous substances lists: 
Component CAS CA MA MN NJ PA 
ANILAZINE101-05-3No No No Yes No 




Not listed under California Proposition 65 




Germany Water Classification 

ANILAZINE (101-05-3)

ID Number 911 , hazard class 3 - severe hazard to waters








Symbol(s)

Xi Irritant

N Dangerous for the Environment

Risk Phrases

R36/38 Irritating to eyes and skin.

R50 Very toxic to aquatic organisms.

R53 May cause long-term adverse effects in the aquatic environment.

Safety Phrases

S2 Keep out of the reach of children.

S22 Do not breathe dust.

S60 This material and its container must be disposed of as hazardous waste.

S61 Avoid release to the environment. Refer to special instructions/ Safety Data Sheets.




Component Analysis - Inventory 
Component CAS# US CA EU AU PH JP KR CN NZ 
ANILAZINE101-05-3No No EIN Yes Yes No Yes No Yes 








Globally Harmonized System of Classification and Labeling (GHS) 

The listed component(s) of this material have been checked for country-specific published classifications according to the Globally Harmonized System of Classification and Labeling (GHS). The results of the queries are displayed below. Please see the individual country listings, as additional interpretations or reference information may be available. For a reference list of H- or P-statements, please visit ChemADVISOR’s website at http://www.chemadvisor.com/product-resources/26-pure-substance-and-mixture-databases/247-ghs-hazard-and-physical-statements 

Australia GHS Classifications 

Classifications below published by Australia's Department of Employment and Workplace Relations, through the Office of the Australian Safety and Compensation Council (ASCC) 
ANILAZINE (101-05-3)

Skin Corrosion/Irritation Category 2 H315 Causes skin irritation

Serious Eye Damage/Eye Irritation Category 2 H319 Causes serious eye irritation

Hazardous to the Aquatic Environment - Acute Category 1 H400 Very toxic to aquatic life

Hazardous to the Aquatic Environment - Chronic Category 1 H410 Very toxic to aquatic life with long lasting effects

Australia GHS Labeling Information 

Labeling information below according to classifications published by Australia's Department of Employment and Workplace Relations, through the Office of the Australian Safety and Compensation Council (ASCC) 
ANILAZINE (101-05-3)

Symbol(s)

 


Signal Word Warning

Hazard(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H410 Very toxic to aquatic life with long lasting effects

Prevention

P280 Wear protective gloves/protective clothing/eye protection/face protection

P264 Wash thoroughly after handling

P273 Avoid release to the environment

Response

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

P337+P313 If eye irritation persists: Get medical advice/attention

P302+P352 IF ON SKIN: Wash with plenty of soap and water

P362+P364 Take off contaminated clothing and wash it before reuse

P332+P313 If skin irritation occurs: Get medical advice/attention

P321 Specific treatment (see label)

P391 Collect spillage

Disposal

P501 Dispose of contents/container in accordance with local/regional/national/international regulations




European Union GHS Classifications 

Classifications below according to Regulation (EC) No 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP) 
ANILAZINE (101-05-3)

Skin Corrosion/Irritation Category 2 H315 Causes skin irritation

Serious Eye Damage/Eye Irritation Category 2 H319 Causes serious eye irritation

Hazardous to the Aquatic Environment - Acute Category 1 H400 Very toxic to aquatic life

Hazardous to the Aquatic Environment - Chronic Category 1 H410 Very toxic to aquatic life with long lasting effects




European Union GHS Labeling Information 

Labeling information below is according to Regulation (EC) No 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP) 
ANILAZINE (101-05-3)

Symbol(s)

 


Signal Word Warning

Hazard(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H410 Very toxic to aquatic life with long lasting effects

Prevention

P280 Wear protective gloves/protective clothing/eye protection/face protection

P264 Wash thoroughly after handling

P273 Avoid release to the environment

Response

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

P337+P313 If eye irritation persists: Get medical advice/attention

P302+P352 IF ON SKIN: Wash with plenty of soap and water

P362+P364 Take off contaminated clothing and wash it before reuse

P332+P313 If skin irritation occurs: Get medical advice/attention

P321 Specific treatment (see label)

P391 Collect spillage

Disposal

P501 Dispose of contents/container in accordance with local/regional/national/international regulations




Indonesia GHS Classifications 

No published information available

This material may be hazardous according to published criteria for classification




Japan GHS Classifications 

Classifications below published under Japan's Chemicals Classification Program according to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) 
ANILAZINE (101-05-3) Approval: 20A2029

Acute toxicity Inhalation - Dust and Mist Category 2 H330 Fatal if inhaled

Serious Eye Damage/Eye Irritation Category 2A H319 Causes serious eye irritation

Hazardous to the Aquatic Environment - Acute Category 1 H400 Very toxic to aquatic life

Hazardous to the Aquatic Environment - Chronic Category 1 H410 Very toxic to aquatic life with long lasting effects




Japan GHS Labeling Information 

Labeling information below according to classifications published by Japan's Chemicals Classification Program according to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) 
ANILAZINE (101-05-3)

Symbol(s)

 


Signal Word Danger

Hazard(s)

H330 Fatal if inhaled

H319 Causes serious eye irritation

H410 Very toxic to aquatic life with long lasting effects

Prevention

P271 Use only outdoors or in a well-ventilated area

P280 Wear protective gloves/protective clothing/eye protection/face protection

P284 Wear respiratory protection

P260 Do not breathe dust/fume/gas/mist/vapours/spray

P264 Wash thoroughly after handling

P273 Avoid release to the environment

Response

P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing

P310 Immediately call a POISON CENTER or doctor/physician

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

P337+P313 If eye irritation persists: Get medical advice/attention

P320 Specific treatment is urgent (see label)

P391 Collect spillage

Storage

P403+P233 Store in a well-ventilated place. Keep container tightly closed

P405 Store locked up

Disposal

P501 Dispose of contents/container in accordance with local/regional/national/international regulations




Korea GHS Classifications 

No published information available

This material may be hazardous according to published criteria for classification




New Zealand GHS Classifications 

No published information available

This material may be hazardous according to published criteria for classification




South Africa GHS Classifications 

No published information available

This material may be hazardous according to published criteria for classification




Taiwan GHS Classifications 

No published information available

This material may be hazardous according to published criteria for classification












Classification 

No classification assigned. 









* * * Section 16 - OTHER INFORMATION  * * *


Key / Legend 

ACGIH - American Conference of Governmental Industrial Hygienists; ADR - European Road Transport; AU - Australia; BOD - Biochemical Oxygen Demand; C - Celsius; CA - Canada; CAS - Chemical Abstracts Service; CERCLA - Comprehensive Environmental Response, Compensation, and Liability Act; CN - China; CPR - Controlled Products Regulations; DFG - Deutsche Forschungsgemeinschaft; DOT - Department of Transportation; DSL - Domestic Substances List; EEC - European Economic Community; EINECS - European Inventory of Existing Commercial Chemical Substances; EPA - Environmental Protection Agency; EU - European Union; F - Fahrenheit; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; ICAO - International Civil Aviation Organization; IDL - Ingredient Disclosure List; IDLH - Immediately Dangerous to Life and Health; IMDG - International Maritime Dangerous Goods; JP - Japan; Kow - Octanol/water partition coefficient; KR - Korea; LEL - Lower Explosive Limit; LOLI - List Of LIsts™ - ChemADVISOR’s Regulatory Database; MAK - Maximum Concentration Value in the Workplace; MEL - Maximum Exposure Limits; NFPA - National Fire Protection Agency; NIOSH - National Institute for Occupational Safety and Health; NJTSR - New Jersey Trade Secret Registry; NTP - National Toxicology Program; NZ - New Zealand; OSHA - Occupational Safety and Health Administration; PH - Philippines; RCRA - Resource Conservation and Recovery Act; RID - European Rail Transport; RTECS - Registry of Toxic Effects of Chemical Substances®; SARA - Superfund Amendments and Reauthorization Act; STEL - Short-term Exposure Limit; TDG - Transportation of Dangerous Goods; TSCA - Toxic Substances Control Act; TWA - Time Weighted Average; UEL - Upper Explosive Limit; US - United States 


Other Information 

Reasonable care has been taken in the preparation of this information; however, the manufacturer makes no warranty whatsoever including the warranty of merchantability, expressed or implied, with respect to this information. The manufacturer makes no representations and assumes no liability for any direct, incidental, consequential, or other such damages resulting from its use or misuse. 

Disclaimer: 

Supplier gives no warranty whatsoever, including the warranties of merchantability or of fitness for a particular purpose. Any product purchased is sold on the assumption the purchaser shall determine the quality and suitability of the product. Supplier expressly disclaims any and all liability for incidental, consequential or any other damages arising out of the use or misuse of this product. No information provided shall be deemed to be a recommendation to use any product in conflict with any existing patent rights. THIS SDS IS TO BE UTILIZED SOLELY AS A REFERENCE DOCUMENT AND IT IS NOT TO BE USED TO SATISFY THE DISTRIBUTION REQUIREMENTS OF OSHA'S HAZARD COMMUNICATION STANDARD (HCS) NOR CANADA'S CONTROLLED PRODUCT REGULATION (CPR). Read the Safety Data Sheet before handling product. Use of any information contained herein is provided at the reader's own risk and thus independent judgment by trained professionals must be utilized at all times. 






Copyright 

Copyright 1984-2016 ChemADVISOR, Inc "RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through Accelrys/Biovia. Portions ©Copyright 2016, U.S. Government. All rights reserved