Safety Data Sheet: Material Name: N,N-DIMETHYLANILINE SDS ID: ohs16070 Issue Date: 2016-06-23 Revision: 2.09

                

N,N-DIMETHYLANILINE

ChemADVISOR, Inc. Stone Quarry Crossing 811 Camp Horne Road, Suite 220 Pittsburgh, PA 15237 E-mail: info@chemadvisor.com MSDS is for reference use only; please contact manufacturer for emergency response information, routine product inquiries and orders.

amines, aromatic 



AMINODIMETHYLBENZENE; BENZENAMINE; (DIMETHYLAMINO)BENZENE; DIMETHYLANILINE; DIMETHYLPHENYLAMINE; DMA; N-PHENYLDIMETHYLAMINE; N-DIMETHYL-ANILINE; N,N-DIMETHYLBENZENEAMINE; N,N-DIMETHYLPHENYLAMINE; N,N-DIMETHYLAMINOBENZENE; NCI-C56428; VERSNELLER NL 63/10; UN 2253; C8H11N

Emergency Overview 

Color:  yellow to brown 

Change in color: changes color on exposure to air

Physical Form: Not available

Odor:  fishy odor 

Health Hazards:  skin irritation, eye irritation, blood damage 

Physical Hazards:  Flash back hazard. Combustible liquid and vapor. 

Short Term:  nausea, vomiting, stomach pain, difficulty breathing, irregular heartbeat, headache, drowsiness, dizziness, visual disturbances, bluish skin color, convulsions, coma 

Long Term:  same as effects reported in short term exposure 

Short Term:  irritation, nausea, vomiting, difficulty breathing, irregular heartbeat, headache, drowsiness, dizziness, bluish skin color, convulsions, coma 

Long Term:  same as effects reported in short term exposure 

Short Term:  irritation (possibly severe) 

Long Term:  same as effects reported in short term exposure 

Short Term:  nausea, vomiting, difficulty breathing, irregular heartbeat, headache, drowsiness, dizziness, bluish skin color, convulsions, coma 

Long Term:  same as effects reported in short term exposure 

CAS EC No Registration No	Component Name Synonyms	1272/2008 (CLP)	Percent
121-69-7 204-493-5 --	N,N-DIMETHYLANILINE	Acute Tox. 3 (Oral) - H301 Acute Tox. 3 (Dermal) - H311 Acute Tox. 3 (Inh.) - H331 Carc. 2 - H351 Aquatic Chronic 2 - H411	100

If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. Get immediate medical attention. 



Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention, if needed. Thoroughly clean and dry contaminated clothing and shoes before reuse. 



Flush eyes with plenty of water for at least 15 minutes. Then get immediate medical attention. 



Contact local poison control center or physician immediately. Never make an unconscious person vomit or drink fluids. When vomiting occurs, keep head lower than hips to help prevent aspiration. If person is unconscious, turn head to side. Get medical attention immediately. 



For ingestion, consider gastric lavage and activated charcoal slurry. 



methylene blue, intravenous; ascorbic acid, intravenous. 









See Section 9 for Flammability Properties 



Moderate fire hazard. The vapor is heavier than air. Vapors or gases may ignite at distant ignition sources and flash back. Vapor/air mixtures are explosive above flash point. 



regular dry chemical, carbon dioxide, water, regular foam, alcohol-resistant foam Large fires: Use regular foam or flood with fine water spray. 



Move container from fire area if it can be done without risk. Cool containers with water spray until well after the fire is out. Stay away from the ends of tanks. For fires in cargo or storage area: Cool containers with water from unmanned hose holder or monitor nozzles until well after fire is out. If this is impossible then take the following precautions: Keep unnecessary people away, isolate hazard area and deny entry. Let the fire burn. Withdraw immediately in case of rising sound from venting safety device or any discoloration of tanks due to fire. For tank, rail car or tank truck: Evacuation radius: 800 meters (1/2 mile). Do not attempt to extinguish fire unless flow of material can be stopped first. Flood with fine water spray. Do not scatter spilled material with high-pressure water streams. Cool containers with water spray until well after the fire is out. Apply water from a protected location or from a safe distance. Avoid inhalation of material or combustion by-products. Stay upwind and keep out of low areas. 









Avoid heat, flames, sparks and other sources of ignition. Do not touch spilled material. Stop leak if possible without personal risk. Reduce vapors with water spray. Small spills: Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal. Small dry spills: Move containers away from spill to a safe area. Large spills: Dike for later disposal. Remove sources of ignition. Keep unnecessary people away, isolate hazard area and deny entry. Ventilate closed spaces before entering. Notify Local Emergency Planning Committee and State Emergency Response Commission for release greater than or equal to RQ (U.S. SARA Section 304). If release occurs in the U.S. and is reportable under CERCLA Section 103, notify the National Response Center at (800)424-8802 (USA) or (202)426-2675 (USA). 









Store and handle in accordance with all current regulations and standards. Subject to storage regulations: U.S. OSHA 29 CFR 1910.106. Grounding and bonding required. Keep separated from incompatible substances. 

Component Exposure Limits 

Biological limit value 



Provide local exhaust ventilation system. Ventilation equipment should be explosion-resistant if explosive concentrations of material are present. Ensure compliance with applicable exposure limits. 



Eyes/Face Wear splash resistant safety goggles. Provide an emergency eye wash fountain and quick drench shower in the immediate work area. 



Wear appropriate chemical resistant clothing. 



Wear appropriate chemical resistant gloves. 



The following respirators and maximum use concentrations are drawn from NIOSH and/or OSHA. 50 ppm Any supplied-air respirator. 100 ppm Any supplied-air respirator operated in a continuous-flow mode. Any self-contained breathing apparatus with a full facepiece. Any supplied-air respirator with a full facepiece. Emergency or planned entry into unknown concentrations or IDLH conditions - Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. Any supplied-air respirator with a full facepiece that is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode. Escape - Any air-purifying full-facepiece respirator (gas mask) with a chin-style, front-mounted or back-mounted organic vapor canister. Any appropriate escape-type, self-contained breathing apparatus. 

Appearance	Not available	Physical State	Liquid
Odor	fishy odor	Color	yellow to brown
Odor Threshold	Not available	pH	Not available
Melting Point	1.5 - 2.5 °C	Boiling Point	193 - 194 °C
Freezing point	Not available	Evaporation Rate	Not available
Boiling Point Range	Not available	Flammability (solid, gas)	Not available
Autoignition	370 °C	Flash Point	62 °C CC
Lower Explosive Limit	1 %	Decomposition	Not available
Upper Explosive Limit	Not available	Vapor Pressure	<1 mmHg at 20 °C
Vapor Density (air=1)	4.17	Specific Gravity (water=1)	0.956
Water Solubility	(slightly soluble)	Partition coefficient: n-octanol/water	Not available
Viscosity	Not available	Solubility (Other)	Not available
Change in color	changes color on exposure to air	Density	Not available
Texture	oily	Molecular Formula	C6-H5-N-(C-H3)2
Molecular Weight	121.18	OSHA Flammability Class	IIIA

alcohol, acetone, benzene, chloroform, ether 













Stable at normal temperatures and pressure. 



Avoid heat, flames, sparks and other sources of ignition. Containers may rupture or explode if exposed to heat. Dangerous gases may accumulate in confined spaces. Keep out of water supplies and sewers. 



acids, peroxides, combustible materials, oxidizing materials, 

N,N-DIMETHYLANILINE: ACIDS (STRONG): Incompatible. DIBENZOYL PEROXIDE: May explode. DIISOPROPYL PEROXYDICARBONATE: May explode. OXIDIZERS (STRONG): Fire and explosion hazard.

oxides of carbon, oxides of nitrogen, anilines 

Thermal decomposition products: carbon monoxide, oxides of nitrogen, aniline.

Will not polymerize. 

Component Analysis - LD50/LC50 

Component Carcinogenicity

In 2-year gavage studies, there was some evidence of carcinogenic activity for male rats as indicated by the increased incidences of sarcomas or osteosarcomas (combined) of the spleen There was equivocal evidence of carcinogenic activity for female mice, as indicated by an increased incidence of squamous cell papillomas of the forestomach (NTP TR-360). 

METHEMOGLOBIN FORMERS: At about 15% concentration of methemoglobin, observable cyanosis of the lips, nose, and earlobes may appear Symptoms may be absent although euphoria, flushed face and headache are common At 25-40%, cyanosis is marked, but little disability occurs except on exertion At 40-60%, symptoms may include weakness, dizziness, lightheadedness, increasingly severe headache, ataxia, rapid, shallow respiration, drowsiness, nausea, vomiting, confusion, lethargy, and stupor Above 60%, dyspnea, respiratory depression, tachycardia or bradycardia, convulsions, and coma may occur Levels above 70% may be fatal.



METHEMOGLOBIN FORMERS Compounds with cumulative properties may produce a persistent, chronic type of methemoglobinemia which is the same as that produced by single large exposures.



N,N-DIMETHYLANILINE: A case of 2 workers who, following an apparently severe exposure, collapsed immediately, were unconscious for eight hours and complained of visual disturbances and intense abdominal pain See information on methemoglobin formers.



METHEMOGLOBIN FORMERS: At about 15% concentration of methemoglobin, observable cyanosis of the lips, nose, and earlobes may appear Symptoms may be absent although euphoria, flushed face, and headache are common At 25-40%, cyanosis is marked, but little disability occurs except on exertion At 40-60%, symptoms may include weakness, dizziness, lightheadedness, increasingly severe headache, ataxia, rapid, shallow respiration, drowsiness, nausea, vomiting, confusion, lethargy, and stupor Above 60%, dyspnea, respiratory depression, tachycardia or bradycardia, convulsions, and coma may occur Levels above 70% may be fatal.



METHEMOGLOBIN FORMERS Compounds with cumulative properties may produce a persistent, chronic type of methemoglobinemia which is the same as that produced by single large exposures.



N,N-DIMETHYLANILINE: May cause irritation The liquid was slightly irritation to the clipped skin of rabbits See information on methemoglobin formers.



N,N-DIMETHYLANILINE: May cause irritation, redness and pain 0.005 mL caused severe burns when instilled in rabbit eyes.



N,N-DIMETHYLANILINE Repeated or prolonged contact may cause conjunctivitis.



METHEMOGLOBIN FORMERS: At about 15% concentration of methemoglobin, observable cyanosis of the lips, nose and earlobes may appear Symptoms may be absent although euphoria, flushed face and headache are common At 25-40%, cyanosis is marked, but little disability occurs except on exertion At 40-60%, symptoms may include weakness, dizziness, lightheadedness, increasingly severe headache, ataxia, rapid, shallow respiration, drowsiness, nausea, vomiting, confusion, lethargy, and stupor Above 60%, dyspnea, respiratory depression, tachycardia or bradycardia, convulsions, and coma may occur Levels above 70% may be fatal.



METHEMOGLOBIN FORMERS Compounds with cumulative properties may produce a persistent chronic type of methemoglobinemia which is the same as that produced by single large exposures.



N,N-DIMETHYLANILINE: Oral administration of 2 grams to guinea pigs has caused weakness, tremors, tonic and clonic convulsions, slowing of respiration and finally death due to respiratory paralysis In two-year gavage studies, there were increased incidences of sarcomas or osteosarcomas (combined) of the spleen in male rats There was an increased indidence of squamous cell papillomas of the forestomach in female mice Compound-related splenic fibrosis, hemisiderosis, and fatty metamorphosis were increased in male rats See information on methemoglobin formers.

Component Analysis - Aquatic Toxicity 

Bioconcentration Factor 

Dispose in accordance with all applicable regulations. 

Component Waste Numbers 

ADR Tunnel Code Restrictions 

Component Marine Pollutants (IMDG) 

SARA Section 311/312 (40 CFR 370 Subparts B and C) 

Not listed under California Proposition 65 

Canadian WHMIS Ingredient Disclosure List (IDL) 

Germany Water Classification 

The listed component(s) of this material have been checked for country-specific published classifications according to the Globally Harmonized System of Classification and Labeling (GHS). The results of the queries are displayed below. Please see the individual country listings, as additional interpretations or reference information may be available. For a reference list of H- or P-statements, please visit ChemADVISOR’s website at http://www.chemadvisor.com/product-resources/26-pure-substance-and-mixture-databases/247-ghs-hazard-and-physical-statements 

Australia GHS Classifications 

Australia GHS Labeling Information 

European Union GHS Classifications 

European Union GHS Labeling Information 

Indonesia GHS Classifications 

Japan GHS Classifications 

Japan GHS Labeling Information 

Korea GHS Classifications 

Korea GHS Labeling Information 

New Zealand GHS Classifications 

New Zealand GHS Labeling Information 

South Africa GHS Classifications 

Taiwan GHS Classifications 

Taiwan GHS Labeling Information 

No classification assigned. 









ACGIH - American Conference of Governmental Industrial Hygienists; ADR - European Road Transport; AU - Australia; BOD - Biochemical Oxygen Demand; C - Celsius; CA - Canada; CAS - Chemical Abstracts Service; CERCLA - Comprehensive Environmental Response, Compensation, and Liability Act; CN - China; CPR - Controlled Products Regulations; DFG - Deutsche Forschungsgemeinschaft; DOT - Department of Transportation; DSL - Domestic Substances List; EEC - European Economic Community; EINECS - European Inventory of Existing Commercial Chemical Substances; EPA - Environmental Protection Agency; EU - European Union; F - Fahrenheit; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; ICAO - International Civil Aviation Organization; IDL - Ingredient Disclosure List; IDLH - Immediately Dangerous to Life and Health; IMDG - International Maritime Dangerous Goods; JP - Japan; Kow - Octanol/water partition coefficient; KR - Korea; LEL - Lower Explosive Limit; LOLI - List Of LIsts™ - ChemADVISOR’s Regulatory Database; MAK - Maximum Concentration Value in the Workplace; MEL - Maximum Exposure Limits; NFPA - National Fire Protection Agency; NIOSH - National Institute for Occupational Safety and Health; NJTSR - New Jersey Trade Secret Registry; NTP - National Toxicology Program; NZ - New Zealand; OSHA - Occupational Safety and Health Administration; PH - Philippines; RCRA - Resource Conservation and Recovery Act; RID - European Rail Transport; RTECS - Registry of Toxic Effects of Chemical Substances®; SARA - Superfund Amendments and Reauthorization Act; STEL - Short-term Exposure Limit; TDG - Transportation of Dangerous Goods; TSCA - Toxic Substances Control Act; TWA - Time Weighted Average; UEL - Upper Explosive Limit; US - United States 



Reasonable care has been taken in the preparation of this information; however, the manufacturer makes no warranty whatsoever including the warranty of merchantability, expressed or implied, with respect to this information. The manufacturer makes no representations and assumes no liability for any direct, incidental, consequential, or other such damages resulting from its use or misuse.  Supplier gives no warranty whatsoever, including the warranties of merchantability or of fitness for a particular purpose. Any product purchased is sold on the assumption the purchaser shall determine the quality and suitability of the product. Supplier expressly disclaims any and all liability for incidental, consequential or any other damages arising out of the use or misuse of this product. No information provided shall be deemed to be a recommendation to use any product in conflict with any existing patent rights. THIS SDS IS TO BE UTILIZED SOLELY AS A REFERENCE DOCUMENT AND IT IS NOT TO BE USED TO SATISFY THE DISTRIBUTION REQUIREMENTS OF OSHA'S HAZARD COMMUNICATION STANDARD (HCS) NOR CANADA'S CONTROLLED PRODUCT REGULATION (CPR). Read the Safety Data Sheet before handling product. Use of any information contained herein is provided at the reader's own risk and thus independent judgment by trained professionals must be utilized at all times. 







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