2-NITROANISOLE

aromatic 

ORTHO-METHOXYNITROBENZENE; 2-METHOXYNITROBENZENE; 2-NITROMETHOXYBENZENE; ORTHO-NITROPHENYL METHYL ETHER; 1-NITRO-2-METHOXYBENZENE; 2-METHOXY-1-NITROBENZENE; ORTHO-NITROANISOLE; ORTHO-NITROBENZENE METHYL ETHER; 1-METHOXY-2-NITROBENZENE; C7H7NO3

Emergency Overview 

Color:  colorless to amber 

Change in color: Not available

Physical Form: liquid

Health Hazards:  suspect cancer hazard (in animals) 

Short Term:  no information is available 

Long Term:  no information is available 

Short Term:  no information is available 

Long Term:  no information is available 

Short Term:  no information is available 

Long Term:  no information is available 

Short Term:  no information on significant adverse effects 

Long Term:  kidney damage, cancer 

If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. Get immediate medical attention. 

Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention, if needed. Thoroughly clean and dry contaminated clothing and shoes before reuse. 

Flush eyes with plenty of water for at least 15 minutes. Then get immediate medical attention. 

If a large amount is swallowed, get medical attention. 

See Section 9 for Flammability Properties 

Slight fire hazard. 

regular dry chemical, carbon dioxide, water, regular foam Large fires: Use regular foam or flood with fine water spray. 

Move container from fire area if it can be done without risk. Do not scatter spilled material with high-pressure water streams. Dike for later disposal. Use extinguishing agents appropriate for surrounding fire. Avoid inhalation of material or combustion by-products. Stay upwind and keep out of low areas. 

Subject to California Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). Keep out of water supplies and sewers. 

Stop leak if possible without personal risk. Small spills: Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal. Keep unnecessary people away, isolate hazard area and deny entry. 

Store and handle in accordance with all current regulations and standards. Keep separated from incompatible substances. 

Component Exposure Limits 

Biological limit value 

Provide local exhaust or process enclosure ventilation system. Ensure compliance with applicable exposure limits. 

Eyes/Face Wear splash resistant safety goggles. Provide an emergency eye wash fountain and quick drench shower in the immediate work area. 

Wear appropriate chemical resistant clothing. 

Wear appropriate chemical resistant gloves. 

Under conditions of frequent use or heavy exposure, respiratory protection may be needed. Respiratory protection is ranked in order from minimum to maximum. Consider warning properties before use. Any chemical cartridge respirator with organic vapor cartridge(s). Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s). Any air-purifying respirator with a full facepiece and an organic vapor canister. For Unknown Concentrations or Immediately Dangerous to Life or Health - Any supplied-air respirator with a full facepiece that is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode. Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. 

alcohol, ether 

Stable at normal temperatures and pressure. 

Avoid heat, flames, sparks and other sources of ignition. Avoid contact with incompatible materials. 

oxidizing materials, 

2-NITROANISOLE: HYDROGEN + CATALYST: Vigorous reaction @ 250 C and 34 bar. OXIDIZERS (STRONG): Fire and explosion hazard. SODIUM HYDROXIDE + ZINC: May explode.

oxides of nitrogen, oxides of carbon 

Thermal decomposition products: oxides of nitrogen.

Will not polymerize. 

Component Analysis - LD50/LC50 

Component Carcinogenicity

Feed studies showed clear evidence of carcinogenic activity in rats based on increased incidences of mononuclear cell leukemia and neoplasms of the urinary bladder, kidney, and large intestine There was clear evidence of carcinogenic activity in male mice based on increased incidences of benign and malignant hepatocellular neoplasms There was some evidence of carcinogenic activity in female mice based on increased incidences of hepatocellular adenomas. 

2-NITROANISOLE No data available.

2-NITROANISOLE No data available.

2-NITROANISOLE No data available.

2-NITROANISOLE No data available.

2-NITROANISOLE No data available.

2-NITROANISOLE No data available.

2-NITROANISOLE The lethal dose reported in rats was 740 mg/kg.

2-NITROANISOLE: Administration to rats produced clear evidence of carcinogenic activity based on increased incidences of benign and malignant neoplasms of the urinary bladder, transitional cell neoplasms of the kidney, benign and malignant neoplasms of the large intestine, and mononuclear cell leukemia Administration to mice produced clear evidence of carcinogenic activity based on increased incidences of benign and malignant hepatocellular neoplasms Administration to female mice produced some evidence of carcinogenic activity based on increased incidences of hepatocellular adenomas Increased severity of nephropathy, increased incidences of focal hyperplasia of the renal tubule epithelium and ulcers of the forestomach, transitional cell hyperplasia of the urinary bladder, focal hyperplasia of the forestomach, and hyperplasia of the transitional epithelium of the kidney pelvis were also seen.

Component Analysis - Aquatic Toxicity 

Bioconcentration Factor 

Dispose in accordance with all applicable regulations. 

Component Waste Numbers 

Component Marine Pollutants (IMDG) 

SARA Section 311/312 (40 CFR 370 Subparts B and C) 

The following statement(s) are provided under the California Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65): 

Canadian WHMIS Ingredient Disclosure List (IDL) 

Germany Water Classification 

REACH List of Substances Subject to Restriction (Annex XVII) - Reg. (EU) No. 1907/2006 

The listed component(s) of this material have been checked for country-specific published classifications according to the Globally Harmonized System of Classification and Labeling (GHS). The results of the queries are displayed below. Please see the individual country listings, as additional interpretations or reference information may be available. For a reference list of H- or P-statements, please visit ChemADVISOR’s website at http://www.chemadvisor.com/product-resources/26-pure-substance-and-mixture-databases/247-ghs-hazard-and-physical-statements 

Australia GHS Classifications 

Australia GHS Labeling Information 

European Union GHS Classifications 

European Union GHS Labeling Information 

Indonesia GHS Classifications 

Japan GHS Classifications 

Japan GHS Labeling Information 

Korea GHS Classifications 

Korea GHS Labeling Information 

New Zealand GHS Classifications 

New Zealand GHS Labeling Information 

South Africa GHS Classifications 

Taiwan GHS Classifications 

Taiwan GHS Labeling Information 

No classification assigned. 

ACGIH - American Conference of Governmental Industrial Hygienists; ADR - European Road Transport; AU - Australia; BOD - Biochemical Oxygen Demand; C - Celsius; CA - Canada; CAS - Chemical Abstracts Service; CERCLA - Comprehensive Environmental Response, Compensation, and Liability Act; CN - China; CPR - Controlled Products Regulations; DFG - Deutsche Forschungsgemeinschaft; DOT - Department of Transportation; DSL - Domestic Substances List; EEC - European Economic Community; EINECS - European Inventory of Existing Commercial Chemical Substances; EPA - Environmental Protection Agency; EU - European Union; F - Fahrenheit; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; ICAO - International Civil Aviation Organization; IDL - Ingredient Disclosure List; IDLH - Immediately Dangerous to Life and Health; IMDG - International Maritime Dangerous Goods; JP - Japan; Kow - Octanol/water partition coefficient; KR - Korea; LEL - Lower Explosive Limit; LOLI - List Of LIsts™ - ChemADVISOR’s Regulatory Database; MAK - Maximum Concentration Value in the Workplace; MEL - Maximum Exposure Limits; NFPA - National Fire Protection Agency; NIOSH - National Institute for Occupational Safety and Health; NJTSR - New Jersey Trade Secret Registry; NTP - National Toxicology Program; NZ - New Zealand; OSHA - Occupational Safety and Health Administration; PH - Philippines; RCRA - Resource Conservation and Recovery Act; RID - European Rail Transport; RTECS - Registry of Toxic Effects of Chemical Substances®; SARA - Superfund Amendments and Reauthorization Act; STEL - Short-term Exposure Limit; TDG - Transportation of Dangerous Goods; TSCA - Toxic Substances Control Act; TWA - Time Weighted Average; UEL - Upper Explosive Limit; US - United States 

Reasonable care has been taken in the preparation of this information; however, the manufacturer makes no warranty whatsoever including the warranty of merchantability, expressed or implied, with respect to this information. The manufacturer makes no representations and assumes no liability for any direct, incidental, consequential, or other such damages resulting from its use or misuse. 

Supplier gives no warranty whatsoever, including the warranties of merchantability or of fitness for a particular purpose. Any product purchased is sold on the assumption the purchaser shall determine the quality and suitability of the product. Supplier expressly disclaims any and all liability for incidental, consequential or any other damages arising out of the use or misuse of this product. No information provided shall be deemed to be a recommendation to use any product in conflict with any existing patent rights. THIS SDS IS TO BE UTILIZED SOLELY AS A REFERENCE DOCUMENT AND IT IS NOT TO BE USED TO SATISFY THE DISTRIBUTION REQUIREMENTS OF OSHA'S HAZARD COMMUNICATION STANDARD (HCS) NOR CANADA'S CONTROLLED PRODUCT REGULATION (CPR). Read the Safety Data Sheet before handling product. Use of any information contained herein is provided at the reader's own risk and thus independent judgment by trained professionals must be utilized at all times. 

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