4-PICOLINE

pyridinyl 

4-METHYLPYRIDINE; PARA-METHYLPYRIDINE; GAMMA-METHYLPYRIDINE; PARA-PICOLINE; GAMMA-PICOLINE; P-METHYLPYRIDINE; P-PICOLINE; UN 2313; C6H7N

Emergency Overview 

Color:  colorless to yellow 

Change in color: hygroscopic

Physical Form: liquid

Odor:  unpleasant odor 

Health Hazards:  harmful if inhaled, harmful on contact with the skin, harmful if swallowed, respiratory tract burns, skin burns, eye burns, mucous membrane burns, central nervous system depression 

Physical Hazards:  Flash back hazard. Combustible liquid and vapor. 

Short Term:  burns, headache, drowsiness, dizziness, loss of coordination 

Long Term:  burns, headache, drowsiness, dizziness, loss of coordination 

Short Term:  burns, absorption may occur, headache, drowsiness, dizziness, loss of coordination 

Long Term:  burns 

Short Term:  burns 

Long Term:  no information on significant adverse effects 

Short Term:  burns 

Long Term:  burns 

If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. If breathing is difficult, oxygen should be administered by qualified personnel. Get immediate medical attention. 

Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get immediate medical attention. Thoroughly clean and dry contaminated clothing before reuse. Destroy contaminated shoes. 

Immediately flush eyes with plenty of water for at least 15 minutes. Then get immediate medical attention. 

Contact local poison control center or physician immediately. Never make an unconscious person vomit or drink fluids. Give large amounts of water or milk. Allow vomiting to occur. When vomiting occurs, keep head lower than hips to help prevent aspiration. If person is unconscious, turn head to side. Get medical attention immediately. 

For inhalation, consider oxygen. Avoid gastric lavage or emesis. 

See Section 9 for Flammability Properties 

Moderate fire hazard. The vapor is heavier than air. Vapors or gases may ignite at distant ignition sources and flash back. Vapor/air mixtures are explosive above flash point. Moderate explosion hazard. 

regular dry chemical, carbon dioxide, water, regular foam, alcohol-resistant foam Large fires: Use regular foam or flood with fine water spray. 

Move container from fire area if it can be done without risk. Do not get water inside container. Cool containers with water spray until well after the fire is out. Stay away from the ends of tanks. Withdraw immediately in case of rising sound from venting safety device or any discoloration of tanks due to fire. For tank, rail car or tank truck, evacuation radius: 800 meters (1/2 mile). Do not attempt to extinguish fire unless flow of material can be stopped first. Cool containers with water spray until well after the fire is out. Apply water from a protected location or from a safe distance. Do not get water directly on material. Large fires: Flood with fine water spray. Reduce vapors with water spray. Avoid inhalation of material or combustion by-products. Stay upwind and keep out of low areas. 

Avoid heat, flames, sparks and other sources of ignition. Do not touch spilled material. Stop leak if possible without personal risk. Reduce vapors with water spray. Do not get water inside container. Small spills: Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal. Large spills: Dike for later disposal. Remove sources of ignition. Keep unnecessary people away, isolate hazard area and deny entry. 

Store and handle in accordance with all current regulations and standards. Subject to storage regulations: U.S. OSHA 29 CFR 1910.106. Grounding and bonding required. Store in a cool, dry place. Store in a tightly closed container. Keep separated from incompatible substances. 

Component Exposure Limits 

Biological limit value 

Provide local exhaust or process enclosure ventilation system. Ventilation equipment should be explosion-resistant if explosive concentrations of material are present. Ensure compliance with applicable exposure limits. 

Eyes/Face Wear splash resistant safety goggles with a faceshield. Provide an emergency eye wash fountain and quick drench shower in the immediate work area. 

Wear appropriate chemical resistant clothing. 

Wear appropriate chemical resistant gloves. 

Under conditions of frequent use or heavy exposure, respiratory protection may be needed. Respiratory protection is ranked in order from minimum to maximum. Consider warning properties before use. Any chemical cartridge respirator with organic vapor cartridge(s). Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s). Any air-purifying respirator with a full facepiece and an organic vapor canister. For Unknown Concentrations or Immediately Dangerous to Life or Health - Any supplied-air respirator with a full facepiece that is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode. Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. 

alcohol, ether, acetone, ether, ethanol 

Stable at normal temperatures and pressure. 

Avoid heat, flames, sparks and other sources of ignition. Minimize contact with material. Keep out of water supplies and sewers. 

acids, halo carbons, oxidizing materials, 

4-PICOLINE: ACIDS: Incompatible. ACID CHLORIDES: Incompatible. CHLOROFORMATES: Incompatible. OXIDIZERS (STRONG): Fire and explosion hazard.

oxides of carbon, nitrogen 

Thermal decomposition products: oxides of carbon, nitrogen. test.

Will not polymerize. 

Component Analysis - LD50/LC50 

Component Carcinogenicity

None of this product's components are listed by ACGIH, IARC, NTP, DFG or OSHA

Alcohol may enhance the toxic effects. 

May cause damage to liver and kidneys. 

CORROSIVE SUBSTANCES: May cause severe irritation of the respiratory tract with coughing, choking, pain and possibly burns of the mucous membranes In some cases, pulmonary edema may develop, either immediately or more often within a period of 5-72 hours The symptoms may include tightness in the chest, dyspnea, frothy sputum, cyanosis, and dizziness Physical findings may include moist rales, low blood pressure and high pulse pressure Severe cases may be fatal.

CORROSIVE SUBSTANCES Depending on the concentration and duration of exposure, repeated or prolonged exposure may cause inflammatory and ulcerative changes in the mouth and possibly bronchial and gastrointestinal disturbances.

4-PICOLINE: May cause sore throat, wheezing, laryngitis, diarrhea, vomiting, weight loss, anemia, central nervous system depression with narcosis, headache, giddiness, drowsiness, and ocular and facial paralysis See information on corrosive substances.

CORROSIVE SUBSTANCES Direct contact may cause severe irritation, pain, and possibly burns.

CORROSIVE SUBSTANCES: Effects depend on concentration and duration of exposure Repeated or prolonged contact may result in dermatitis or effects similar to acute exposure.

4-PICOLINE: Skin absorption may occur resulting in same effects as detailed in inhalation See information on corrosive substances.

CORROSIVE SUBSTANCES: Direct contact may cause severe irritation, pain and burns, possibly severe The degree of injury depends on the concentration and duration of contact The full extent of the injury may not be immediately apparent.

CORROSIVE SUBSTANCES: Effects depend on concentration and duration of exposure Repeated or prolonged contact may result in conjunctivitis or effects as in acute exposure.

4-PICOLINE See information on corrosive substances.

CORROSIVE SUBSTANCES: May cause immediate pain and severe burns of the mucous membranes There may be discoloration of the tissues Swallowing and speech may be difficult at first and then almost impossible The effects on the esophagus and gastrointestinal tract may range from irritation to severe corrosion Edema of the epiglottis and shock may occur.

CORROSIVE SUBSTANCES Depending on the concentration, repeated ingestion may cause effects as with acute ingestion.

4-PICOLINE: May cause abdominal pain, nausea, vomiting, and diarrhea See information on corrosive substances.

Component Analysis - Aquatic Toxicity 

Subject to disposal regulations: U.S. EPA 40 CFR 262. Hazardous Waste Number(s): D001. Dispose in accordance with all applicable regulations. 

Component Waste Numbers 

Component Marine Pollutants (IMDG) 

SARA Section 311/312 (40 CFR 370 Subparts B and C) 

Not listed under California Proposition 65 

Canadian WHMIS Ingredient Disclosure List (IDL) 

Germany Water Classification 

The listed component(s) of this material have been checked for country-specific published classifications according to the Globally Harmonized System of Classification and Labeling (GHS). The results of the queries are displayed below. Please see the individual country listings, as additional interpretations or reference information may be available. For a reference list of H- or P-statements, please visit ChemADVISOR’s website at http://www.chemadvisor.com/product-resources/26-pure-substance-and-mixture-databases/247-ghs-hazard-and-physical-statements 

Australia GHS Classifications 

Australia GHS Labeling Information 

European Union GHS Classifications 

European Union GHS Labeling Information 

Indonesia GHS Classifications 

Japan GHS Classifications 

Japan GHS Labeling Information 

Korea GHS Classifications 

Korea GHS Labeling Information 

New Zealand GHS Classifications 

New Zealand GHS Labeling Information 

South Africa GHS Classifications 

Taiwan GHS Classifications 

Taiwan GHS Labeling Information 

No classification assigned. 

ACGIH - American Conference of Governmental Industrial Hygienists; ADR - European Road Transport; AU - Australia; BOD - Biochemical Oxygen Demand; C - Celsius; CA - Canada; CAS - Chemical Abstracts Service; CERCLA - Comprehensive Environmental Response, Compensation, and Liability Act; CN - China; CPR - Controlled Products Regulations; DFG - Deutsche Forschungsgemeinschaft; DOT - Department of Transportation; DSL - Domestic Substances List; EEC - European Economic Community; EINECS - European Inventory of Existing Commercial Chemical Substances; EPA - Environmental Protection Agency; EU - European Union; F - Fahrenheit; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; ICAO - International Civil Aviation Organization; IDL - Ingredient Disclosure List; IDLH - Immediately Dangerous to Life and Health; IMDG - International Maritime Dangerous Goods; JP - Japan; Kow - Octanol/water partition coefficient; KR - Korea; LEL - Lower Explosive Limit; LOLI - List Of LIsts™ - ChemADVISOR’s Regulatory Database; MAK - Maximum Concentration Value in the Workplace; MEL - Maximum Exposure Limits; NFPA - National Fire Protection Agency; NIOSH - National Institute for Occupational Safety and Health; NJTSR - New Jersey Trade Secret Registry; NTP - National Toxicology Program; NZ - New Zealand; OSHA - Occupational Safety and Health Administration; PH - Philippines; RCRA - Resource Conservation and Recovery Act; RID - European Rail Transport; RTECS - Registry of Toxic Effects of Chemical Substances®; SARA - Superfund Amendments and Reauthorization Act; STEL - Short-term Exposure Limit; TDG - Transportation of Dangerous Goods; TSCA - Toxic Substances Control Act; TWA - Time Weighted Average; UEL - Upper Explosive Limit; US - United States 

Reasonable care has been taken in the preparation of this information; however, the manufacturer makes no warranty whatsoever including the warranty of merchantability, expressed or implied, with respect to this information. The manufacturer makes no representations and assumes no liability for any direct, incidental, consequential, or other such damages resulting from its use or misuse. 

Supplier gives no warranty whatsoever, including the warranties of merchantability or of fitness for a particular purpose. Any product purchased is sold on the assumption the purchaser shall determine the quality and suitability of the product. Supplier expressly disclaims any and all liability for incidental, consequential or any other damages arising out of the use or misuse of this product. No information provided shall be deemed to be a recommendation to use any product in conflict with any existing patent rights. THIS SDS IS TO BE UTILIZED SOLELY AS A REFERENCE DOCUMENT AND IT IS NOT TO BE USED TO SATISFY THE DISTRIBUTION REQUIREMENTS OF OSHA'S HAZARD COMMUNICATION STANDARD (HCS) NOR CANADA'S CONTROLLED PRODUCT REGULATION (CPR). Read the Safety Data Sheet before handling product. Use of any information contained herein is provided at the reader's own risk and thus independent judgment by trained professionals must be utilized at all times. 

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